Functional impacts of 5-hydroxymethylcytosine, 5-formylcytosine, and 5-carboxycytosine at a single hemi-modified CpG dinucleotide in a gene promoter

Enzymatic oxidation of 5-methylcytosine (5-mC) in the CpG dinucleotides to 5-hydroxymethylcytosine (5-hmC), 5-formylcytosine (5-fC) and 5-carboxycytosine (5-caC) has central role in the process of active DNA demethylation and epigenetic reprogramming in mammals. However, it is not known whether the...

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Detalles Bibliográficos
Autores principales: Kitsera, Nataliya, Allgayer, Julia, Parsa, Edris, Geier, Nadine, Rossa, Martin, Carell, Thomas, Khobta, Andriy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737506/
https://www.ncbi.nlm.nih.gov/pubmed/28977475
http://dx.doi.org/10.1093/nar/gkx718

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737506/
https://www.ncbi.nlm.nih.gov/pubmed/28977475
http://dx.doi.org/10.1093/nar/gkx718

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