Dynamic nucleoplasmic and nucleolar localization of mammalian RNase H1 in response to RNAP I transcriptional R-loops

An R-loop is a DNA:RNA hybrid formed during transcription when a DNA duplex is invaded by a nascent RNA transcript. R-loops accumulate in nucleoli during RNA polymerase I (RNAP I) transcription. Here, we report that mammalian RNase H1 enriches in nucleoli and co-localizes with R-loops in cultured hu...

Descripción completa

Detalles Bibliográficos
Autores principales: Shen, Wen, Sun, Hong, De Hoyos, Cheryl L., Bailey, Jeffrey K., Liang, Xue-hai, Crooke, Stanley T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737507/
https://www.ncbi.nlm.nih.gov/pubmed/28977560
http://dx.doi.org/10.1093/nar/gkx710

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737507/
https://www.ncbi.nlm.nih.gov/pubmed/28977560
http://dx.doi.org/10.1093/nar/gkx710

Ejemplares similares