PARP1 controls KLF4-mediated telomerase expression in stem cells and cancer cells

Telomerase is highly expressed in cancer and embryonic stem cells (ESCs) and implicated in controlling genome integrity, cancer formation and stemness. Previous studies identified that Krüppel-like transcription factor 4 (KLF4) activates telomerase reverse transcriptase (TERT) expression and contrib...

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Detalles Bibliográficos
Autores principales: Hsieh, Meng-Hsun, Chen, Yi-Ting, Chen, You-Tzung, Lee, Yi-Hsuan, Lu, Jean, Chien, Chung-Liang, Chen, Hsin-Fu, Ho, Hong-Nerng, Yu, Chia-Jung, Wang, Zhao-Qi, Teng, Shu-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737510/
https://www.ncbi.nlm.nih.gov/pubmed/28985359
http://dx.doi.org/10.1093/nar/gkx683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737510/
https://www.ncbi.nlm.nih.gov/pubmed/28985359
http://dx.doi.org/10.1093/nar/gkx683

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