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Resolving sugar puckers in RNA excited states exposes slow modes of repuckering dynamics

Recent studies have shown that RNAs exist in dynamic equilibrium with short-lived low-abundance ‘excited states’ that form by reshuffling base pairs in and around non-canonical motifs. These conformational states are proposed to be rich in non-canonical motifs and to play roles in the folding and re...

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Detalles Bibliográficos
Autores principales: Clay, Mary C., Ganser, Laura R., Merriman, Dawn K., Al-Hashimi, Hashim M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737546/
https://www.ncbi.nlm.nih.gov/pubmed/28609788
http://dx.doi.org/10.1093/nar/gkx525