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HiTAD: detecting the structural and functional hierarchies of topologically associating domains from chromatin interactions

A current question in the high-order organization of chromatin is whether topologically associating domains (TADs) are distinct from other hierarchical chromatin domains. However, due to the unclear TAD definition in tradition, the structural and functional uniqueness of TAD is not well studied. In...

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Detalles Bibliográficos
Autores principales: Wang, Xiao-Tao, Cui, Wang, Peng, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737579/
https://www.ncbi.nlm.nih.gov/pubmed/28977529
http://dx.doi.org/10.1093/nar/gkx735