How proteins bind to DNA: target discrimination and dynamic sequence search by the telomeric protein TRF1

Target search as performed by DNA-binding proteins is a complex process, in which multiple factors contribute to both thermodynamic discrimination of the target sequence from overwhelmingly abundant off-target sites and kinetic acceleration of dynamic sequence interrogation. TRF1, the protein that b...

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Detalles Bibliográficos
Autores principales: Wieczór, Miłosz, Czub, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737604/
https://www.ncbi.nlm.nih.gov/pubmed/28633355
http://dx.doi.org/10.1093/nar/gkx534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737604/
https://www.ncbi.nlm.nih.gov/pubmed/28633355
http://dx.doi.org/10.1093/nar/gkx534

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