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The RNA chaperone La promotes pre-tRNA maturation via indiscriminate binding of both native and misfolded targets

Non-coding RNAs have critical roles in biological processes, and RNA chaperones can promote their folding into the native shape required for their function. La proteins are a class of highly abundant RNA chaperones that contact pre-tRNAs and other RNA polymerase III transcripts via their common UUU-...

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Detalles Bibliográficos
Autores principales: Vakiloroayaei, Ana, Shah, Neha S., Oeffinger, Marlene, Bayfield, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737608/
https://www.ncbi.nlm.nih.gov/pubmed/28977649
http://dx.doi.org/10.1093/nar/gkx764