Bacillus subtilis DNA polymerases, PolC and DnaE, are required for both leading and lagging strand synthesis in SPP1 origin-dependent DNA replication

Firmicutes have two distinct replicative DNA polymerases, the PolC leading strand polymerase, and PolC and DnaE synthesizing the lagging strand. We have reconstituted in vitro Bacillus subtilis bacteriophage SPP1 θ-type DNA replication, which initiates unidirectionally at oriL. With this system we s...

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Detalles Bibliográficos
Autores principales: Seco, Elena M., Ayora, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737612/
https://www.ncbi.nlm.nih.gov/pubmed/28575448
http://dx.doi.org/10.1093/nar/gkx493

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737612/
https://www.ncbi.nlm.nih.gov/pubmed/28575448
http://dx.doi.org/10.1093/nar/gkx493

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