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Lithium and Tamoxifen Modulate Behavior and Protein Kinase C Activity in the Animal Model of Mania Induced by Ouabain
BACKGROUND: The intracerebroventricular injection of ouabain, a specific inhibitor of the Na(+)/K(+)-adenosine-triphosphatase (Na(+)/K(+)-ATPase) enzyme, induces hyperactivity in rats in a putative animal model of mania. Several evidences have suggested that the protein kinase C signaling pathway is...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737643/ https://www.ncbi.nlm.nih.gov/pubmed/29020306 http://dx.doi.org/10.1093/ijnp/pyx049 |