Lithium and Tamoxifen Modulate Behavior and Protein Kinase C Activity in the Animal Model of Mania Induced by Ouabain

BACKGROUND: The intracerebroventricular injection of ouabain, a specific inhibitor of the Na(+)/K(+)-adenosine-triphosphatase (Na(+)/K(+)-ATPase) enzyme, induces hyperactivity in rats in a putative animal model of mania. Several evidences have suggested that the protein kinase C signaling pathway is...

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Detalles Bibliográficos
Autores principales: Valvassori, Samira S, Dal-Pont, Gustavo C, Resende, Wilson R, Varela, Roger B, Peterle, Bruna R, Gava, Fernanda F, Mina, Francielle G, Cararo, José H, Carvalho, André F, Quevedo, João
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Regular Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737643/
https://www.ncbi.nlm.nih.gov/pubmed/29020306
http://dx.doi.org/10.1093/ijnp/pyx049

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