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New insights into a classic aptamer: binding sites, cooperativity and more sensitive adenosine detection
The DNA aptamer for adenosine (also for AMP and ATP) is a highly conserved sequence that has recurred in a few selections. It it a widely used model aptamer for biosensor development, and its nuclear magnetic resonance structure shows that each aptamer binds two AMP molecules. In this work, each bin...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737652/ https://www.ncbi.nlm.nih.gov/pubmed/28591844 http://dx.doi.org/10.1093/nar/gkx517 |