Functional details of the Mycobacterium tuberculosis VapBC26 toxin-antitoxin system based on a structural study: insights into unique binding and antibiotic peptides

Toxin-antitoxin (TA) systems are essential for bacterial persistence under stressful conditions. In particular, Mycobacterium tuberculosis express VapBC TA genes that encode the stable VapC toxin and the labile VapB antitoxin. Under normal conditions, these proteins interact to form a non-toxic TA c...

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Detalles Bibliográficos
Autores principales: Kang, Sung-Min, Kim, Do-Hee, Lee, Ki-Young, Park, Sung Jean, Yoon, Hye-Jin, Lee, Sang Jae, Im, Hookang, Lee, Bong-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737657/
https://www.ncbi.nlm.nih.gov/pubmed/28575388
http://dx.doi.org/10.1093/nar/gkx489

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737657/
https://www.ncbi.nlm.nih.gov/pubmed/28575388
http://dx.doi.org/10.1093/nar/gkx489

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