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Distinct roles of Pcf11 zinc-binding domains in pre-mRNA 3′-end processing

New transcripts generated by RNA polymerase II (RNAPII) are generally processed in order to form mature mRNAs. Two key processing steps include a precise cleavage within the 3′ end of the pre-mRNA, and the subsequent polymerization of adenosines to produce the poly(A) tail. In yeast, these two funct...

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Detalles Bibliográficos
Autores principales: Guéguéniat, Julia, Dupin, Adrien F., Stojko, Johan, Beaurepaire, Lionel, Cianférani, Sarah, Mackereth, Cameron D., Minvielle-Sébastia, Lionel, Fribourg, Sébastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737669/
https://www.ncbi.nlm.nih.gov/pubmed/28973460
http://dx.doi.org/10.1093/nar/gkx674