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CRISPR-mediated isolation of specific megabase segments of genomic DNA

Megabase-sized, complex, repetitive regions of genomes are poorly studied, due to the technical and computational challenges inherent to both assembling precise reference sequences and accurately assessing structural variation across contiguous megabase DNA regions. Here we describe a strategy to ov...

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Detalles Bibliográficos
Autores principales: Bennett-Baker, Pamela E., Mueller, Jacob L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737698/
https://www.ncbi.nlm.nih.gov/pubmed/28977642
http://dx.doi.org/10.1093/nar/gkx749