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CRISPR-mediated isolation of specific megabase segments of genomic DNA
Megabase-sized, complex, repetitive regions of genomes are poorly studied, due to the technical and computational challenges inherent to both assembling precise reference sequences and accurately assessing structural variation across contiguous megabase DNA regions. Here we describe a strategy to ov...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737698/ https://www.ncbi.nlm.nih.gov/pubmed/28977642 http://dx.doi.org/10.1093/nar/gkx749 |