Identification of Plagl1/Zac1 binding sites and target genes establishes its role in the regulation of extracellular matrix genes and the imprinted gene network

PLAGL1/ZAC1 undergoes parental genomic imprinting, is paternally expressed, and is a member of the imprinted gene network (IGN). It encodes a zinc finger transcription factor with anti-proliferative activity and is a candidate tumor suppressor gene on 6q24 whose expression is frequently lost in vari...

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Detalles Bibliográficos
Autores principales: Varrault, Annie, Dantec, Christelle, Le Digarcher, Anne, Chotard, Laëtitia, Bilanges, Benoit, Parrinello, Hugues, Dubois, Emeric, Rialle, Stéphanie, Severac, Dany, Bouschet, Tristan, Journot, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737700/
https://www.ncbi.nlm.nih.gov/pubmed/28985358
http://dx.doi.org/10.1093/nar/gkx672

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737700/
https://www.ncbi.nlm.nih.gov/pubmed/28985358
http://dx.doi.org/10.1093/nar/gkx672

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