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Improvement of In Vivo Expression of Genes Delivered by Self-Amplifying RNA Using Vaccinia Virus Immune Evasion Proteins

Among nucleic acid–based delivery platforms, self-amplifying RNA (saRNA) vectors are of increasing interest for applications such as transient expression of recombinant proteins and vaccination. saRNA is safe and, due to its capability to amplify intracellularly, high protein levels can be produced...

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Detalles Bibliográficos
Autores principales: Beissert, Tim, Koste, Lars, Perkovic, Mario, Walzer, Kerstin C., Erbar, Stephanie, Selmi, Abderraouf, Diken, Mustafa, Kreiter, Sebastian, Türeci, Özlem, Sahin, Ugur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737720/
https://www.ncbi.nlm.nih.gov/pubmed/28877647
http://dx.doi.org/10.1089/hum.2017.121