Separation and assembly of deep sequencing data into discrete sub-population genomes

Sequence heterogeneity is a common characteristic of RNA viruses that is often referred to as sub-populations or quasispecies. Traditional techniques used for assembly of short sequence reads produced by deep sequencing, such as de-novo assemblers, ignore the underlying diversity. Here, we introduce...

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Detalles Bibliográficos
Autores principales: Karagiannis, Konstantinos, Simonyan, Vahan, Chumakov, Konstantin, Mazumder, Raja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737798/
https://www.ncbi.nlm.nih.gov/pubmed/28977510
http://dx.doi.org/10.1093/nar/gkx755

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737798/
https://www.ncbi.nlm.nih.gov/pubmed/28977510
http://dx.doi.org/10.1093/nar/gkx755

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