Chromosome-scale mega-haplotypes enable digital karyotyping of cancer aneuploidy

Genomic instability is a frequently occurring feature of cancer that involves large-scale structural alterations. These somatic changes in chromosome structure include duplication of entire chromosome arms and aneuploidy where chromosomes are duplicated beyond normal diploid content. However, the ac...

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Detalles Bibliográficos
Autores principales: Bell, John M., Lau, Billy T., Greer, Stephanie U., Wood-Bouwens, Christina, Xia, Li C., Connolly, Ian D., Gephart, Melanie H., Ji, Hanlee P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737808/
https://www.ncbi.nlm.nih.gov/pubmed/28977555
http://dx.doi.org/10.1093/nar/gkx712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737808/
https://www.ncbi.nlm.nih.gov/pubmed/28977555
http://dx.doi.org/10.1093/nar/gkx712

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