Fractionation iCLIP detects persistent SR protein binding to conserved, retained introns in chromatin, nucleoplasm and cytoplasm

RNA binding proteins (RBPs) regulate the lives of all RNAs from transcription, processing, and function to decay. How RNA–protein interactions change over time and space to support these roles is poorly understood. Towards this end, we sought to determine how two SR proteins—SRSF3 and SRSF7, regulat...

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Detalles Bibliográficos
Autores principales: Brugiolo, Mattia, Botti, Valentina, Liu, Na, Müller-McNicoll, Michaela, Neugebauer, Karla M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737842/
https://www.ncbi.nlm.nih.gov/pubmed/28977534
http://dx.doi.org/10.1093/nar/gkx671

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737842/
https://www.ncbi.nlm.nih.gov/pubmed/28977534
http://dx.doi.org/10.1093/nar/gkx671

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