CgII cleaves DNA using a mechanism distinct from other ATP-dependent restriction endonucleases

The restriction endonuclease CglI from Corynebacterium glutamicum recognizes an asymmetric 5′-GCCGC-3′ site and cleaves the DNA 7 and 6/7 nucleotides downstream on the top and bottom DNA strands, respectively, in an NTP-hydrolysis dependent reaction. CglI is composed of two different proteins: an en...

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Detalles Bibliográficos
Autores principales: Toliusis, Paulius, Zaremba, Mindaugas, Silanskas, Arunas, Szczelkun, Mark D., Siksnys, Virginijus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737866/
https://www.ncbi.nlm.nih.gov/pubmed/28854738
http://dx.doi.org/10.1093/nar/gkx580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737866/
https://www.ncbi.nlm.nih.gov/pubmed/28854738
http://dx.doi.org/10.1093/nar/gkx580

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