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The structure of transcription termination factor Nrd1 reveals an original mode for GUAA recognition

Transcription termination of non-coding RNAs is regulated in yeast by a complex of three RNA binding proteins: Nrd1, Nab3 and Sen1. Nrd1 is central in this process by interacting with Rbp1 of RNA polymerase II, Trf4 of TRAMP and GUAA/G terminator sequences. We lack structural data for the last of th...

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Detalles Bibliográficos
Autores principales: Franco-Echevarría, Elsa, González-Polo, Noelia, Zorrilla, Silvia, Martínez-Lumbreras, Santiago, Santiveri, Clara M., Campos-Olivas, Ramón, Sánchez, Mar, Calvo, Olga, González, Beatriz, Pérez-Cañadillas, José Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737872/
https://www.ncbi.nlm.nih.gov/pubmed/28973465
http://dx.doi.org/10.1093/nar/gkx685