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Down-regulation of miR-9* in the peripheral leukocytes of Huntington’s disease patients

BACKGROUND: Huntington’s disease (HD), caused by expansion of a polyglutamine tract within HUNTINGTIN (HTT) protein, is an autosomal dominant neurodegenerative disease associated with a progressive neurodegeneration of striatum and cerebral cortex. Although a few studies have identified substantial...

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Detalles Bibliográficos
Autores principales: Chang, Kuo-Hsuan, Wu, Yih-Ru, Chen, Chiung-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737985/
https://www.ncbi.nlm.nih.gov/pubmed/29258536
http://dx.doi.org/10.1186/s13023-017-0742-x