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Probing the putative α7 nAChR/NMDAR complex in human and murine cortex and hippocampus: Different degrees of complex formation in healthy and Alzheimer brain tissue

α7 nicotinic acetylcholine receptors (nAChRs) and N-methyl-D-aspartate receptors (NMDARs) are key mediators of central cholinergic and glutamatergic neurotransmission, respectively. In addition to numerous well-established functional interactions between α7 nAChRs and NMDARs, the two receptors have...

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Detalles Bibliográficos
Autores principales: Elnagar, Mohamed R., Walls, Anne Byriel, Helal, Gouda K., Hamada, Farid M., Thomsen, Morten Skøtt, Jensen, Anders A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738045/
https://www.ncbi.nlm.nih.gov/pubmed/29261717
http://dx.doi.org/10.1371/journal.pone.0189513