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Whole genome microarray analysis of neural progenitor C17.2 cells during differentiation and validation of 30 neural mRNA biomarkers for estimation of developmental neurotoxicity

Despite its high relevance, developmental neurotoxicity (DNT) is one of the least studied forms of toxicity. Current guidelines for DNT testing are based on in vivo testing and they require extensive resources. Transcriptomic approaches using relevant in vitro models have been suggested as a useful...

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Detalles Bibliográficos
Autores principales: Attoff, Kristina, Gliga, Anda, Lundqvist, Jessica, Norinder, Ulf, Forsby, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738075/
https://www.ncbi.nlm.nih.gov/pubmed/29261810
http://dx.doi.org/10.1371/journal.pone.0190066