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Energy homeostasis in leptin deficient Lep(ob/ob) mice
Maintenance of reduced body weight is associated both with reduced energy expenditure per unit metabolic mass and increased hunger in mice and humans. Lowered circulating leptin concentration, due to decreased fat mass, provides a primary signal for this response. However, leptin deficient (Lep(ob/o...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738099/ https://www.ncbi.nlm.nih.gov/pubmed/29261744 http://dx.doi.org/10.1371/journal.pone.0189784 |