Knockdown of myeloid cell hypoxia-inducible factor-1α ameliorates the acute pathology in DSS-induced colitis

Inflammation and hypoxia are hallmarks of inflammatory bowel disease. Low oxygen levels activate hypoxia-inducible factors as central transcriptional regulators of cellular responses to hypoxia, particularly in myeloid cells where hypoxia-inducible factors control immune cell function and survival....

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Detalles Bibliográficos
Autores principales: Bäcker, Veronika, Cheung, Fung-Yi, Siveke, Jens T., Fandrey, Joachim, Winning, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738114/
https://www.ncbi.nlm.nih.gov/pubmed/29261815
http://dx.doi.org/10.1371/journal.pone.0190074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738114/
https://www.ncbi.nlm.nih.gov/pubmed/29261815
http://dx.doi.org/10.1371/journal.pone.0190074

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