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Interpreting ambiguous ‘trace’ results in Schistosoma mansoni CCA Tests: Estimating sensitivity and specificity of ambiguous results with no gold standard

BACKGROUND: The development of new diagnostics is an important tool in the fight against disease. Latent Class Analysis (LCA) is used to estimate the sensitivity and specificity of tests in the absence of a gold standard. The main field diagnostic for Schistosoma mansoni infection, Kato-Katz (KK), i...

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Detalles Bibliográficos
Autores principales: Clements, Michelle N., Donnelly, Christl A., Fenwick, Alan, Kabatereine, Narcis B., Knowles, Sarah C. L., Meité, Aboulaye, N'Goran, Eliézer K., Nalule, Yolisa, Nogaro, Sarah, Phillips, Anna E., Tukahebwa, Edridah Muheki, Fleming, Fiona M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738141/
https://www.ncbi.nlm.nih.gov/pubmed/29220354
http://dx.doi.org/10.1371/journal.pntd.0006102