Lytic viral replication and immunopathology in a cytomegalovirus-induced mouse model of secondary hemophagocytic lymphohistiocytosis

BACKGROUND: Hemophagocytic lymphohistiocytosis (HLH) is a rare immunological disorder caused by unbridled activation of T cells and macrophages, culminating in a life-threatening cytokine storm. A genetic and acquired subtype are distinguished, termed primary and secondary HLH, respectively. Clinica...

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Detalles Bibliográficos
Autores principales: Brisse, Ellen, Imbrechts, Maya, Mitera, Tania, Vandenhaute, Jessica, Wouters, Carine H., Snoeck, Robert, Andrei, Graciela, Matthys, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738214/
https://www.ncbi.nlm.nih.gov/pubmed/29258535
http://dx.doi.org/10.1186/s12985-017-0908-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738214/
https://www.ncbi.nlm.nih.gov/pubmed/29258535
http://dx.doi.org/10.1186/s12985-017-0908-0

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