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miR-105/93-3p promotes chemoresistance and circulating miR-105/93-3p acts as a diagnostic biomarker for triple negative breast cancer

BACKGROUND: Triple negative breast cancer (TNBC) lacks both early detection biomarkers and viable targeted therapeutics. Moreover, chemotherapy only produces 20–30% pathologic complete response. Because miRNAs are frequently dysregulated in breast cancer and have broad tissue effects, individual or...

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Detalles Bibliográficos
Autores principales: Li, Hao-Yi, Liang, Jui-Lin, Kuo, Yao-Lung, Lee, Hao-Hsien, Calkins, Marcus J., Chang, Hong-Tai, Lin, Forn-Chia, Chen, Yu-Chia, Hsu, Tai-I, Hsiao, Michael, Ger, Luo-Ping, Lu, Pei-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738224/
https://www.ncbi.nlm.nih.gov/pubmed/29258605
http://dx.doi.org/10.1186/s13058-017-0918-2