Treatment with a Non-toxic, Self-replicating Anti-prion Delays or Prevents Prion Disease In vivo

Transmissible Spongiform Encephalopathies (TSEs) are fatal neurological disorders caused by prions, which are composed of a misfolded protein (PrP(Sc)) that self-propagates in the brain of infected individuals by converting the normal prion protein (PrP(C)) into the pathological isoform. Here, we re...

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Detalles Bibliográficos
Autores principales: Diaz-Espinoza, Rodrigo, Morales, Rodrigo, Concha-Marambio, Luis, Moreno-Gonzalez, Ines, Moda, Fabio, Soto, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738294/
https://www.ncbi.nlm.nih.gov/pubmed/28630454
http://dx.doi.org/10.1038/mp.2017.84

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738294/
https://www.ncbi.nlm.nih.gov/pubmed/28630454
http://dx.doi.org/10.1038/mp.2017.84

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