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Treatment with a Non-toxic, Self-replicating Anti-prion Delays or Prevents Prion Disease In vivo
Transmissible Spongiform Encephalopathies (TSEs) are fatal neurological disorders caused by prions, which are composed of a misfolded protein (PrP(Sc)) that self-propagates in the brain of infected individuals by converting the normal prion protein (PrP(C)) into the pathological isoform. Here, we re...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738294/ https://www.ncbi.nlm.nih.gov/pubmed/28630454 http://dx.doi.org/10.1038/mp.2017.84 |