Cargando…

Identifying the ubiquitination targets of E6AP by orthogonal ubiquitin transfer

E3 ubiquitin (UB) ligases are the ending modules of the E1–E2-E3 cascades that transfer UB to cellular proteins and regulate their biological functions. Identifying the substrates of an E3 holds the key to elucidate its role in cell regulation. Here, we construct an orthogonal UB transfer (OUT) casc...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yiyang, Liu, Xianpeng, Zhou, Li, Duong, Duc, Bhuripanyo, Karan, Zhao, Bo, Zhou, Han, Liu, Ruochuan, Bi, Yingtao, Kiyokawa, Hiroaki, Yin, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738348/
https://www.ncbi.nlm.nih.gov/pubmed/29263404
http://dx.doi.org/10.1038/s41467-017-01974-7