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Evidence of novel miR-34a-based therapeutic approaches for multiple myeloma treatment

MiR-34a acts as tumor suppressor microRNA (miRNA) in several cancers, including multiple myeloma (MM), by controlling the expression of target proteins involved in cell cycle, differentiation and apoptosis. Here, we have investigated the combination between miR-34a and γ-secretase inhibitor (γSI), S...

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Detalles Bibliográficos
Autores principales: Zarone, Mayra Rachele, Misso, Gabriella, Grimaldi, Anna, Zappavigna, Silvia, Russo, Margherita, Amler, Evzen, Di Martino, Maria Teresa, Amodio, Nicola, Tagliaferri, Pierosandro, Tassone, Pierfrancesco, Caraglia, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738363/
https://www.ncbi.nlm.nih.gov/pubmed/29263373
http://dx.doi.org/10.1038/s41598-017-18186-0