Cargando…
Evidence of novel miR-34a-based therapeutic approaches for multiple myeloma treatment
MiR-34a acts as tumor suppressor microRNA (miRNA) in several cancers, including multiple myeloma (MM), by controlling the expression of target proteins involved in cell cycle, differentiation and apoptosis. Here, we have investigated the combination between miR-34a and γ-secretase inhibitor (γSI), S...
Autores principales: | Zarone, Mayra Rachele, Misso, Gabriella, Grimaldi, Anna, Zappavigna, Silvia, Russo, Margherita, Amler, Evzen, Di Martino, Maria Teresa, Amodio, Nicola, Tagliaferri, Pierosandro, Tassone, Pierfrancesco, Caraglia, Michele |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738363/ https://www.ncbi.nlm.nih.gov/pubmed/29263373 http://dx.doi.org/10.1038/s41598-017-18186-0 |
Ejemplares similares
-
miR-125b Upregulates miR-34a and Sequentially Activates Stress Adaption and Cell Death Mechanisms in Multiple Myeloma
por: Misso, Gabriella, et al.
Publicado: (2019) -
Mir-34: A New Weapon Against Cancer?
por: Misso, Gabriella, et al.
Publicado: (2014) -
Transferrin-Conjugated SNALPs Encapsulating 2′-O-Methylated miR-34a for the Treatment of Multiple Myeloma
por: Scognamiglio, Immacolata, et al.
Publicado: (2014) -
In Vivo Activity of MiR-34a Mimics Delivered by Stable Nucleic Acid Lipid Particles (SNALPs) against Multiple Myeloma
por: Di Martino, Maria Teresa, et al.
Publicado: (2014) -
DNA-demethylating and anti-tumor activity of synthetic miR-29b mimics in multiple
myeloma
por: Amodio, Nicola, et al.
Publicado: (2012)