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Genome-wide association study identifies a missense variant at APOA5 for coronary artery disease in Multi-Ethnic Cohorts from Southeast Asia

Recent genome-wide association studies (GWAS) have identified multiple loci associated with coronary artery disease (CAD) among predominantly Europeans. However, their relevance to multi-ethnic populations from Southeast Asia is largely unknown. We performed a meta-analysis of four GWAS comprising t...

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Detalles Bibliográficos
Autores principales: Han, Yi, Dorajoo, Rajkumar, Chang, Xuling, Wang, Ling, Khor, Chiea-Chuen, Sim, Xueling, Cheng, Ching-Yu, Shi, Yuan, Tham, Yih Chung, Zhao, Wanting, Chee, Miao Ling, Sabanayagam, Charumathi, Chee, Miao Li, Tan, Nicholas, Wong, Tien Yin, Tai, E-Shyong, Liu, Jianjun, Goh, Daniel Y. T., Yuan, Jian-Min, Koh, Woon-Puay, van Dam, Rob M., Low, Adrian F., Chan, Mark Yan-Yee, Friedlander, Yechiel, Heng, Chew-Kiat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738399/
https://www.ncbi.nlm.nih.gov/pubmed/29263402
http://dx.doi.org/10.1038/s41598-017-18214-z