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p53 and cyclin G cooperate in mediating genome stability in somatic cells of Drosophila

One of the key players in genome surveillance is the tumour suppressor p53 mediating the adaptive response to a multitude of stress signals. Here we identify Cyclin G (CycG) as co-factor of p53-mediated genome stability. CycG has been shown before to be involved in double-strand break repair during...

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Detalles Bibliográficos
Autores principales: Bayer, Fabienne E., Zimmermann, Mirjam, Fischer, Patrick, Gromoll, Christian, Preiss, Anette, Nagel, Anja C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738409/
https://www.ncbi.nlm.nih.gov/pubmed/29263364
http://dx.doi.org/10.1038/s41598-017-17973-z