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Convergent microevolution of Cryptococcus neoformans hypervirulence in the laboratory and the clinic
Reference strains are a key component of laboratory research, providing a common background allowing for comparisons across a community of researchers. However, laboratory passage of these strains has been shown to lead to reduced fitness and the attenuation of virulence in some species. In this stu...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738413/ https://www.ncbi.nlm.nih.gov/pubmed/29263343 http://dx.doi.org/10.1038/s41598-017-18106-2 |