Cargando…
Convergent microevolution of Cryptococcus neoformans hypervirulence in the laboratory and the clinic
Reference strains are a key component of laboratory research, providing a common background allowing for comparisons across a community of researchers. However, laboratory passage of these strains has been shown to lead to reduced fitness and the attenuation of virulence in some species. In this stu...
Autores principales: | Arras, Samantha D. M., Ormerod, Kate L., Erpf, Paige E., Espinosa, Monica I., Carpenter, Alex C., Blundell, Ross D., Stowasser, Samantha R., Schulz, Benjamin L., Tanurdzic, Milos, Fraser, James A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738413/ https://www.ncbi.nlm.nih.gov/pubmed/29263343 http://dx.doi.org/10.1038/s41598-017-18106-2 |
Ejemplares similares
-
Sirtuins in the phylum Basidiomycota: A role in virulence in Cryptococcus neoformans
por: Arras, Samantha D. M., et al.
Publicado: (2017) -
A Genomic Safe Haven for Mutant Complementation in Cryptococcus neoformans
por: Arras, Samantha D. M., et al.
Publicado: (2015) -
Chemical Inhibitors of Non-Homologous End Joining Increase Targeted Construct Integration in Cryptococcus neoformans
por: Arras, Samantha D. M., et al.
Publicado: (2016) -
Comparative Genomics of Serial Isolates of Cryptococcus neoformans Reveals Gene Associated With Carbon Utilization and Virulence
por: Ormerod, Kate L., et al.
Publicado: (2013) -
Targeted Genome Editing via CRISPR in the Pathogen Cryptococcus neoformans
por: Arras, Samantha D. M., et al.
Publicado: (2016)