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Runx2 mediated Induction of Novel Targets ST2 and Runx3 Leads to Cooperative Regulation of Hypertrophic Differentiation in ATDC5 Chondrocytes

Knowledge concerning expression and function of Suppression of Tumorigenicity 2 (ST2) in chondrocytes is at present, limited. Analysis of murine growth plates and ATDC5 chondrocytes indicated peak expression of the ST2 transmembrane receptor (ST2L) and soluble (sST2) isoforms during the hypertrophic...

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Detalles Bibliográficos
Autores principales: Bonyadi Rad, Ehsan, Musumeci, Giuseppe, Pichler, Karin, Heidary, Maryam, Szychlinska, Marta Anna, Castrogiovanni, Paola, Marth, Egon, Böhm, Christina, Srinivasaiah, Sriveena, Krönke, Gerhard, Weinberg, Annelie, Schäfer, Ute
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738421/
https://www.ncbi.nlm.nih.gov/pubmed/29263341
http://dx.doi.org/10.1038/s41598-017-18044-z