NAIP/NLRC4 inflammasome activation in MRP8(+) cells is sufficient to cause systemic inflammatory disease

Inflammasomes are cytosolic multiprotein complexes that initiate protective immunity in response to infection, and can also drive auto-inflammatory diseases, but the cell types and signalling pathways that cause these diseases remain poorly understood. Inflammasomes are broadly expressed in haematop...

Descripción completa

Detalles Bibliográficos
Autores principales: Nichols, Randilea D., von Moltke, Jakob, Vance, Russell E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738432/
https://www.ncbi.nlm.nih.gov/pubmed/29263322
http://dx.doi.org/10.1038/s41467-017-02266-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738432/
https://www.ncbi.nlm.nih.gov/pubmed/29263322
http://dx.doi.org/10.1038/s41467-017-02266-w

Ejemplares similares