Recombinant influenza H9N2 virus with a substitution of H3 hemagglutinin transmembrane domain showed enhanced immunogenicity in mice and chicken

In recent years, avian influenza virus H9N2 undergoing antigenic drift represents a threat to poultry farming as well as public health. Current vaccines are restricted to inactivated vaccine strains and their related variants. In this study, a recombinant H9N2 (H9N2-TM) strain with a replaced H3 hem...

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Detalles Bibliográficos
Autores principales: Zhang, Yun, Wei, Ying, Liu, Kang, Huang, Mengjiao, Li, Ran, Wang, Yang, Liu, Qiliang, Zheng, Jing, Xue, Chunyi, Cao, Yongchang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738434/
https://www.ncbi.nlm.nih.gov/pubmed/29263359
http://dx.doi.org/10.1038/s41598-017-18054-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738434/
https://www.ncbi.nlm.nih.gov/pubmed/29263359
http://dx.doi.org/10.1038/s41598-017-18054-x

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