The activity of myeloid cell-specific VHH immunotoxins is target-, epitope-, subset- and organ dependent

The central role of myeloid cells in driving autoimmune diseases and cancer has raised interest in manipulating their function or depleting them for therapeutic benefits. To achieve this, antibodies are used to antagonize differentiation, survival and polarization signals or to kill target cells, fo...

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Detalles Bibliográficos
Autores principales: Bachran, Christopher, Schröder, Matthias, Conrad, Lena, Cragnolini, Juan J., Tafesse, Fikadu G., Helming, Laura, Ploegh, Hidde L., Swee, Lee Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738442/
https://www.ncbi.nlm.nih.gov/pubmed/29263417
http://dx.doi.org/10.1038/s41598-017-17948-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738442/
https://www.ncbi.nlm.nih.gov/pubmed/29263417
http://dx.doi.org/10.1038/s41598-017-17948-0

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