Sulforaphane reverses gefitinib tolerance in human lung cancer cells via modulation of sonic hedgehog signaling

Gefitinib is a targeted anticancer drug that was developed as an effective clinical therapy for lung cancer. Numerous patients develop gefitinib resistance in response to treatment. Sulforaphane (SFN) is present in cruciferous vegetables, and has been demonstrated to inhibit the malignant growth of...

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Detalles Bibliográficos
Autores principales: Wang, Fanping, Wang, Wenjun, Li, Junpeng, Zhang, Jingjing, Wang, Xia, Wang, Mingyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738694/
https://www.ncbi.nlm.nih.gov/pubmed/29285189
http://dx.doi.org/10.3892/ol.2017.7293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738694/
https://www.ncbi.nlm.nih.gov/pubmed/29285189
http://dx.doi.org/10.3892/ol.2017.7293

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