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Sulforaphane reverses gefitinib tolerance in human lung cancer cells via modulation of sonic hedgehog signaling
Gefitinib is a targeted anticancer drug that was developed as an effective clinical therapy for lung cancer. Numerous patients develop gefitinib resistance in response to treatment. Sulforaphane (SFN) is present in cruciferous vegetables, and has been demonstrated to inhibit the malignant growth of...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738694/ https://www.ncbi.nlm.nih.gov/pubmed/29285189 http://dx.doi.org/10.3892/ol.2017.7293 |