Cargando…

Effects of a naturally occurring amino acid substitution in bovine PrP: a model for inherited prion disease in a natural host species

OBJECTIVE: The most common hereditary prion disease is human Creutzfeldt-Jakob disease (CJD), associated with a mutation in the prion gene resulting in a glutamic acid to lysine substitution at position 200 (E200K) in the prion protein. Models of E200K CJD in transgenic mice have proven interesting...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vrentas, Catherine E., Greenlee, Justin J., Foster, Gregory H., West, James, Jahnke, Marianna M., Schmidt, Mark T., Nicholson, Eric M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Note
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738711/ https://www.ncbi.nlm.nih.gov/pubmed/29262866 http://dx.doi.org/10.1186/s13104-017-3085-8

Ejemplares similares

Relationships between PrP(Sc) Stability and Incubation Time for United States Scrapie Isolates in a Natural Host System
por: Vrentas, Catherine E., et al.
Publicado: (2012)

Pathologic and biochemical characterization of PrP(Sc) from elk with PRNP polymorphisms at codon 132 after experimental infection with the chronic wasting disease agent
por: Moore, S. Jo, et al.
Publicado: (2018)

The Structure of PrP(Sc) Prions
por: Wille, Holger, et al.
Publicado: (2018)

Oral Prion Neuroinvasion Occurs Independently of PrP(C) Expression in the Gut Epithelium
por: Marshall, Alison, et al.
Publicado: (2018)

Stability properties of PrP(Sc) from cattle with experimental transmissible spongiform encephalopathies: use of a rapid whole homogenate, protease-free assay
por: Vrentas, Catherine E, et al.
Publicado: (2013)

Accumulation of Pathological Prion Protein PrP(Sc) in the Skin of Animals with Experimental and Natural Scrapie
por: Thomzig, Achim, et al.
Publicado: (2007)

Prion protein (PrP) gene-knockout cell lines: insight into functions of the PrP
por: Sakudo, Akikazu, et al.
Publicado: (2015)

Exploration of the Main Sites for the Transformation of Normal Prion Protein (PrP(C)) into Pathogenic Prion Protein (PrP(sc))
por: Liu, Xi-Lin, et al.
Publicado: (2017)

A Comparison of Classical and H-Type Bovine Spongiform Encephalopathy Associated with E211K Prion Protein Polymorphism in Wild-Type and EK211 Cattle Following Intracranial Inoculation
por: Moore, S. Jo, et al.
Publicado: (2016)

Heterogeneity of Abnormal Prion Protein (PrP(Sc)) in Murine Scrapie Prions Determined by PrP(Sc)-Specific Monoclonal Antibodies
por: USHIKI-KAKU, Yuko, et al.
Publicado: (2013)

Mammalian prion propagation in PrP transgenic Drosophila
por: Thackray, Alana M, et al.
Publicado: (2018)

Anti-Prion Drug mPPIg5 Inhibits PrP(C) Conversion to PrP(Sc)
por: McCarthy, James M., et al.
Publicado: (2013)

Infectivity-associated PrP(Sc) and disease duration-associated PrP(Sc) of mouse BSE prions
por: Miyazawa, Kohtaro, et al.
Publicado: (2015)

The native state of prion protein (PrP) directly inhibits formation of PrP-amyloid fibrils in vitro
por: Honda, Ryo P., et al.
Publicado: (2017)

Differential Accumulation of Misfolded Prion Strains in Natural Hosts of Prion Diseases
por: Lambert, Zoe J., et al.
Publicado: (2021)

Prion protein—Semisynthetic prion protein (PrP) variants with posttranslational modifications
por: Hackl, Stefanie, et al.
Publicado: (2019)

Prion protein amino acid sequence influences formation of authentic synthetic PrP(Sc)
por: Block, Alyssa J., et al.
Publicado: (2023)

PrP(Sc )detection in formalin-fixed paraffin-embedded tissue by ELISA
por: Nicholson, Eric M, et al.
Publicado: (2011)

The Functional Role of Prion Protein (PrP(C)) on Autophagy
por: Shin, Hae-Young, et al.
Publicado: (2013)

PrP(Sc) formation and clearance as determinants of prion tropism
por: Shikiya, Ronald A., et al.
Publicado: (2017)

The Multifaceted Functions of Prion Protein (PrP(C)) in Cancer
por: Abi Nahed, Roland, et al.
Publicado: (2023)

Small Protease Sensitive Oligomers of PrP(Sc) in Distinct Human Prions Determine Conversion Rate of PrP(C)
por: Kim, Chae, et al.
Publicado: (2012)

Glimepiride Reduces the Expression of PrP(C), Prevents PrP(Sc) Formation and Protects against Prion Mediated Neurotoxicity
por: Bate, Clive, et al.
Publicado: (2009)

A Camelid Anti-PrP Antibody Abrogates PrP(Sc) Replication in Prion-Permissive Neuroblastoma Cell Lines
por: Jones, Daryl Rhys, et al.
Publicado: (2010)

Identifying critical sites of PrP(c)-PrP(Sc) interaction in prion-infected cells by dominant-negative inhibition
por: Taguchi, Yuzuru, et al.
Publicado: (2013)

PrP aggregation can be seeded by pre-formed recombinant PrP amyloid fibrils without the replication of infectious prions
por: Barron, Rona M., et al.
Publicado: (2016)

Mouse-Hamster Chimeric Prion Protein (PrP) Devoid of N-Terminal Residues 23-88 Restores Susceptibility to 22L Prions, but Not to RML Prions in PrP-Knockout Mice
por: Uchiyama, Keiji, et al.
Publicado: (2014)

Novel Strain of the Chronic Wasting Disease Agent Isolated From Experimentally Inoculated Elk With LL132 Prion Protein
por: Moore, Jo, et al.
Publicado: (2020)

Goats naturally devoid of PrP(C) are resistant to scrapie
por: Salvesen, Øyvind, et al.
Publicado: (2020)

The Octarepeat Region of the Prion Protein Is Conformationally Altered in PrP(Sc)
por: Yam, Alice Y., et al.
Publicado: (2010)

PrP(Sc)-Specific Antibodies with the Ability to Immunodetect Prion Oligomers
por: Tayebi, Mourad, et al.
Publicado: (2011)

Evidence That Bank Vole PrP Is a Universal Acceptor for Prions
por: Watts, Joel C., et al.
Publicado: (2014)

Inflammatory response of microglia to prions is controlled by sialylation of PrP(Sc)
por: Srivastava, Saurabh, et al.
Publicado: (2018)

The prion 2018 round tables (I): the structure of PrP(Sc)
por: Baskakov, Ilia V., et al.
Publicado: (2019)

Ovine recombinant PrP as an inhibitor of ruminant prion propagation in vitro
por: Workman, Rob G., et al.
Publicado: (2017)

Genetic human prion disease modelled in PrP transgenic Drosophila
por: Thackray, Alana M., et al.
Publicado: (2017)

Genetic modulation of CWD prion propagation in cervid PrP Drosophila
por: Thackray, Alana M., et al.
Publicado: (2023)

Nanopore Analysis of Wild-Type and Mutant Prion Protein (PrP(C)): Single Molecule Discrimination and PrP(C) Kinetics
por: Jetha, Nahid N., et al.
Publicado: (2013)

PrP(ST), a Soluble, Protease Resistant and Truncated PrP Form Features in the Pathogenesis of a Genetic Prion Disease
por: Friedman-Levi, Yael, et al.
Publicado: (2013)

Sulfated Dextrans Enhance In Vitro Amplification of Bovine Spongiform Encephalopathy PrP(Sc) and Enable Ultrasensitive Detection of Bovine PrP(Sc)
por: Murayama, Yuichi, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_b83mdmg39ckalnk10074jot99g