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The oncogenic role of circPVT1 in head and neck squamous cell carcinoma is mediated through the mutant p53/YAP/TEAD transcription-competent complex

BACKGROUND: Circular RNAs are a class of endogenous RNAs with various functions in eukaryotic cells. Worthy of note, circular RNAs play a critical role in cancer. Currently, nothing is known about their role in head and neck squamous cell carcinoma (HNSCC). The identification of circular RNAs in HNS...

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Detalles Bibliográficos
Autores principales: Verduci, Lorena, Ferraiuolo, Maria, Sacconi, Andrea, Ganci, Federica, Vitale, Jlenia, Colombo, Teresa, Paci, Paola, Strano, Sabrina, Macino, Giuseppe, Rajewsky, Nikolaus, Blandino, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738800/
https://www.ncbi.nlm.nih.gov/pubmed/29262850
http://dx.doi.org/10.1186/s13059-017-1368-y