Cargando…
Establishment and evaluation of four different types of patient-derived xenograft models
BACKGROUND: Patient-derived xenografts (PDX) have a biologically stable in tumor architecture, drug responsiveness, mutational status and global gene-expression patterns. Numerous PDX models have been established to date, however their thorough characterization regarding the tumor formation and rate...
Autores principales: | , , , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738885/ https://www.ncbi.nlm.nih.gov/pubmed/29296105 http://dx.doi.org/10.1186/s12935-017-0497-4 |