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HIF-1alpha and infectious diseases: a new frontier for the development of new therapies

The aim of this review is to show the significant role of HIF-1alpha in inflammatory and infectious diseases. Hypoxia is a physiological characteristic of a wide range of diseases from cancer to infection. Cellular hypoxia is sensed by oxygen-sensitive hydrolase enzymes, which control the protein st...

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Detalles Bibliográficos
Autores principales: dos Santos, Sânia Alves, de Andrade, Dahir Ramos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto de Medicina Tropical 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738998/
https://www.ncbi.nlm.nih.gov/pubmed/29267600
http://dx.doi.org/10.1590/S1678-9946201759092