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HIF-1alpha and infectious diseases: a new frontier for the development of new therapies
The aim of this review is to show the significant role of HIF-1alpha in inflammatory and infectious diseases. Hypoxia is a physiological characteristic of a wide range of diseases from cancer to infection. Cellular hypoxia is sensed by oxygen-sensitive hydrolase enzymes, which control the protein st...
Autores principales: | dos Santos, Sânia Alves, de Andrade, Dahir Ramos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Instituto de Medicina Tropical
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738998/ https://www.ncbi.nlm.nih.gov/pubmed/29267600 http://dx.doi.org/10.1590/S1678-9946201759092 |
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